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Research has demonstrated that NCOA4 knockdown reduces intracellular iron levels and lipid peroxidation, thereby attenuating zinc nanoparticle-induced cell death ( 2+ production under normal cellular conditions, potentially playing a key role in regulating organismal iron homeostasis and inhibiting Fenton reactions ( 5.2 Antioxidant therapy Oxidative stress can induce varying degrees of damage to organisms
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