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5 Antioxidant defense mechanisms in sperm Spermatozoa are uniquely specialized cells essential for the process of fertilization, yet they exhibit a pronounced susceptibility to oxidative stress due to their distinct biological properties

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After prolonged physical exertion, glutathione neutralizes reactive oxygen species (ROS) produced during the Krebs cycle, effectively preventing the lipid peroxidation of mitochondrial membranes and allowing them to recover and maintain efficient ATP production without suffering from premature fatigue or permanent oxidative damage.