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Vitamin D 3 : The first step involved in the activation of vitamin D 3 is a 25-hydroxylation which is catalysed by the 25-hydroxylase in the liver and then by other enzymes

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“Oxidative stress is an imbalance between oxidants and antioxidants in favor of the oxidants, leading to a disruption of redox signaling and control and/or molecular damage” (Sies, 2015) that harm lipids, proteins and DNA (Schieber and Chandel, 2014)