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Gross Clinical Assessment Assessment included edema (involving the face, upper and lower lip, snout, paws and scrotum (presented with extreme cyanosis)) that may be prominent, scored from 0 to 3 (0—without swelling, 1—mild swelling, 2—moderate swelling and 3—severe swelling), poor respiration as respiratory rate [5] and the number of fatalities after one or two applications of isoprenaline