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found that sunitinib produced cardiac toxicity via the involvement of fibrotic and inflammation processes mediated by transcription factor NF-kB, and they also reported that l-carnitine showed a protective effect against secondary fibrotic process, cardiac inflammation, and arterial hypertension induced with sunitinib in Wistar rats [83]

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The incorporation of targeted nutritional support alongside exercise regimens may further amplify these beneficial effects

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