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Therefore, the objective of the present review was to systematically map out the body of existing literature on therapeutic controversies over the use of antioxidant supplements during cancer treatment in order to identify type of antioxidant supplements that have been commonly given for patients, treatment outcomes reported, summarize the safety and effectiveness of these supplements during cancer treatment in the various clinical settings and opportunities for further research

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These analogs [BXT-series are being developed by Oxis International, Foster City, CA ( have been shown to be protective in a limited number of cell culture systems [35] and animal models of human disease (Table 1)