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Potent analogues of somatostatin (peptide hormone consisting of 14 amino acids, found in δ cells of the pancreas as well as in hypothalamic and other gastrointestinal cells) including octreotide (sandostatin) have been developed for the treatment of acromegaly, gigantism, thyrotropinoma, diarrhea and flushing episodes associated with carcinoid syndrome, and diarrhea in patients with vasoactive intestinal peptide-secreting tumors (VIPomas) [33]

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Data and statistics In the 60 th , the prevalence of ASD was estimated to be around 4-5 in 10000, today this number is around 100 (or even more) in 10000 people[6,7] and some authors, even reported a prevalence of 3.6%[7]