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Despite this physiological importance, native amylin has historically been a difficult research tool because of its strong amyloidogenic tendency: the peptide aggregates rapidly at physiological pH into β-sheet-rich fibrils, forming the amyloid deposits characteristic of type-2 diabetic pancreatic islets

Alpha lipoic acid

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NAD+ repletion improves muscle function in muscular dystrophy and counters global PARylation

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